Anti-SOX2 Polyclonal Antibody - SAlexa Fluor 750
Cat: K009480P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-SOX2 Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6657 | 【Swiss Prot】：P48431 |
| 【Tested applications】：WB,ELISA,FCM,IF,ICC,IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg/Test. ICC 1:100. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human SOX2 | |
| 【Public Immunogen Range】：227-317/317aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation.
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