Anti-ITGA5 Polyclonal Antibody - SAlexa Fluor 405
Cat: K009486P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-ITGA5 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3678 | 【Swiss Prot】：P08648 |
| 【Tested applications】：IF,IHC,WB,ELISA | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human ITGA5 | |
| 【Public Immunogen Range】：1021-1099/1099aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5); in platelets as glycoprotein IcIIa; and in fibroblasts as extracellular matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell surface mediated signalling.
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