Anti-DVL1 Polyclonal Antibody - FITC
Cat: K009492P - FITC
Summary:
| 【Product name】：Anti-DVL1 Polyclonal Antibody - FITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：1855 | 【Swiss Prot】：O14640 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human DVL1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
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