Anti-SOCS7 Polyclonal Antibody - Cy3
Cat: K009536P - Cy3
Summary:
| 【Product name】：Anti-SOCS7 Polyclonal Antibody - Cy3 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：30837 | 【Swiss Prot】：O14512 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human SOCS7 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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