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Anti-Notch 2 Polyclonal Antibody - SAlexa Fluor 680
Cat: K009552P - SAlexa Fluor 680
Summary:
【Product name】:Anti-Notch 2 Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4853 【Swiss Prot】:Q04721
【Species reactivity】:Mouse
【Tested applications】:ELISA,IF,IHC
【Immunogen】:A synthetic peptide of human Notch 2
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
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