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Anti-IL2RG Polyclonal Antibody - SAlexa Fluor 633
Cat: K009563P - SAlexa Fluor 633
Summary:
【Product name】:Anti-IL2RG Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:3561 【Swiss Prot】:P31785
【Species reactivity】:Human
【Tested applications】:ELISA,FCM,ICC
【Immunogen】:A synthetic peptide of human IL2RG
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
Interleukin 2 (IL2) receptor gamma chain (IL5212R gamma) is a cell surface glycoprotein expressed by a variety of leukocytes including T cells, B cells, NK cells, monocytes, macrophages, and neutrophils. IL2R gamma is also known as CD132, common cytokine receptor gamma chain, and gamma c. IL2R gamma forms complexes with other cell surface proteins including CD25 (IL2R alpha), CD122 (IL2R beta), CD124 (IL4R alpha), CD127 (IL7R), and others. IL2R gamma complexed with other cell surface proteins forms receptors for the cytokines IL2, IL4, IL7, IL9, and IL15. Acting through the IL2R gamma containing complexes, these cytokines regulate lymphocyte development and activation. Chemical cross linking experiments reveal that IL2R gamma is able to bind cytokines only when complexed with these other cell surface proteins.
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