Anti-Phospho-IRF7(Ser471+Ser472) Polyclonal Antibody
Cat: K009591P
Summary:
| 【Product name】：Anti-Phospho-IRF7(Ser471+Ser472) Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3665 | 【Swiss Prot】：Q92985 |
| 【Tested applications】：WB,IHC,ELISA,ICC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. ICC 1:100. | |
| 【Immunogen】：A synthetic peptide of human IRF7 around the phosphorylation site of Ser471/472 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) in IFN promoters and in the Q promoter (Qp) of EBV nuclear antigen 1 (EBNA1). Functions as a molecular switch for antiviral activity. Activated by phosphorylation in response to infection. Activation leads to nuclear retention, DNA binding, and derepression of transactivation ability.
Verified picture:
Western blot analysis with Phospho-IRF7 (Ser471 + Ser472) antibody diluted at 1:300;Lane: Mouse Uterus Mouse Large intestine.
Immunohistochemistry of paraffin-embedded Human brain glioma with Phospho-IRF7(Ser471+Ser472) antibody diluted at 1:300
Immunohistochemistry of paraffin-embedded human brain glioma with Phospho-IRF7 (Ser471 + Ser472) antibody diluted at 1:400.
Immunofluorescence analysis of HepG2 cell using Phospho-IRF7 (Ser471 + Ser472) antibody diluted at 1:100.