Anti-POU5F1 Polyclonal Antibody
Cat: K009615P
Summary:
| 【Product name】：Anti-POU5F1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5460 | 【Swiss Prot】：Q01860 |
| 【Tested applications】：ELISA,FCM,IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. FCM 1μg /Test. | |
| 【Immunogen】：A synthetic peptide of human POU5F1 | |
| 【Public Immunogen Range】：201-300/360aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq].
Verified picture:
Western blot analysis with Oct-4B/OCT4B-190 antibody diluted at 1:1000;Lane: Mouse Cerebrum Mouse Heart Mouse Cerebellum Mouse Testis Rat Cerebrum Rat Heart Rat Cerebellum.
Immunohistochemistry of paraffin-embedded rat cerebellum with Oct-4B antibody diluted at 1:200.