Anti-CD45 Polyclonal Antibody - SAlexa Fluor 405
Cat: K009649P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-CD45 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5788 | 【Swiss Prot】：P08575 |
| 【Tested applications】：ELISA,FCM | |
| 【Recommended dilution】：ELISA 1:5000-10000. FCM 1μg/Test. | |
| 【Immunogen】：A synthetic peptide of human CD45 | |
| 【Public Immunogen Range】：401-500/1304aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
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