Anti-MAPT Polyclonal Antibody - SAlexa Fluor 350
Cat: K009701P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-MAPT Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4137 | 【Swiss Prot】：P10636 |
| 【Species reactivity】：Rat,Human | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human MAPT | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Verified picture: