Anti-OPG Polyclonal Antibody - SAlexa Fluor 680
Cat: K009702P - SAlexa Fluor 680
Summary:
| 【Product name】：Anti-OPG Polyclonal Antibody - SAlexa Fluor 680 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：4982 | 【Swiss Prot】：O00300 |
| 【Species reactivity】：Rat,Mouse,Human | |
| 【Tested applications】：ELISA,IF,IHC,WB | |
| 【Immunogen】：A synthetic peptide of human OPG | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
Verified picture: