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Anti-QARS Polyclonal Antibody
Cat: K108861P
Summary:
【Product name】:Anti-QARS Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5859 【Swiss Prot】:P47897
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:WB,IHC,IF
【Immunogen】:Recombinant protein of human QARS
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. In metazoans, 9 aminoacyl-tRNA synthetases specific for glutamine (gln), glutamic acid (glu), and 7 other amino acids are associated within a multienzyme complex. Although present in eukaryotes, glutaminyl-tRNA synthetase (QARS) is absent from many prokaryotes, mitochondria, and chloroplasts, in which Gln-tRNA(Gln) is formed by transamidation of the misacylated Glu-tRNA(Gln). Glutaminyl-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with QARS antibody diluted at 1:200
Western blot analysis with QARS antibody diluted at 1:2000;Lane: 293T,Hela,MCF7,MDA-MB-231,A549,SKOV3,HepG2,Mouse testis