Anti-ILK Polyclonal Antibody
Cat: K108927P
Summary:
| 【Product name】：Anti-ILK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：3611 | 【Swiss Prot】：Q13418 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of Human ILK | |
| 【Public Immunogen Range】：195-245/452aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded Human endometrial cancer with ILK antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human stomach cancer with ILK antibody diluted at 1:100.