Anti-TNFRSF1A Polyclonal Antibody
Cat: K108969P
Summary:
| 【Product name】：Anti-TNFRSF1A Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：7132 | 【Swiss Prot】：P19438 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB,IF,IHC | |
| 【Immunogen】：A synthetic peptide of human TNFRSF1A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with TNFRSF1A antibody diluted at 1:100
Western blot analysis with TNFRSF1A antibody diluted at 1:2000;Lane: Jurkat,Human liver cancer
Immunofluorescence analysis of HepG2 cells using TNFRSF1A antibody diluted at 1:100