Anti-PDK3 Polyclonal Antibody - RBITC
Cat: K109019P - RBITC
Summary:
| 【Product name】：Anti-PDK3 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5165 | 【Swiss Prot】：Q15120 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PDK3 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.
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