Anti-TESC Polyclonal Antibody
Cat: K109035P
Summary:
| 【Product name】：Anti-TESC Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：54997 | 【Swiss Prot】：Q96BS2 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB | |
| 【Immunogen】：Recombinant protein of human TESC | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
Verified picture:
Western blot analysis with TESC antibody diluted at 1:2000;Lane:U937,HepG2,A549,Rat brain,Hela