Anti-APAF1 Polyclonal Antibody
Cat: K109159P
Summary:
| 【Product name】：Anti-APAF1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：317 | 【Swiss Prot】：O14727 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC | |
| 【Immunogen】：A synthetic peptide of human APAF1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis
Verified picture:
Immunohistochemistry of paraffin-embedded
Human stomach cancer with APAF1 antibody diluted at 1:80