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Anti-APAF1 Polyclonal Antibody - SAlexa Fluor 680
Cat: K109159P - SAlexa Fluor 680
Summary:
【Product name】:Anti-APAF1 Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:317 【Swiss Prot】:O14727
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of human APAF1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis
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