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Anti-TINF2 Polyclonal Antibody
Cat: K109180P
Summary:
【Product name】:Anti-TINF2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:26277 【Swiss Prot】:Q9BSI4
【Species reactivity】:Human,Mouse
【Tested applications】:WB
【Immunogen】:A synthetic peptide of human TINF2
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
Verified picture:
Western blot analysis with TINF2 antibody diluted at 1:2000;Lane: Hela,HUVEC,Mouse skeletal muscle