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Anti-DOK1 Polyclonal Antibody
Cat: K109181P
Summary:
【Product name】:Anti-DOK1 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:1796 【Swiss Prot】:Q99704
【Species reactivity】:Human
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of human DOK1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with DOK1 antibody diluted at 1:80