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Anti-ORC4 Polyclonal Antibody
Cat: K109217P
Summary:
【Product name】:Anti-ORC4 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:5000 【Swiss Prot】:O43929
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:IHC
【Immunogen】:A synthetic peptide of human ORC4
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
Verified picture:
Immunohistochemistry of paraffin-embedded Human liver cancer with ORC4 antibody diluted at 1:80