Anti-MAEL Polyclonal Antibody
Cat: K109306P
Summary:
| 【Product name】：Anti-MAEL Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：84944 | 【Swiss Prot】：Q96JY0 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：IHC | |
| 【Immunogen】：Recombinant protein of human MAEL | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage (By similarity).
Verified picture:
Immunohistochemistry of paraffin-embedded Human berast cancer with MAEL antibody diluted at 1:100