Anti-TTL Polyclonal Antibody - SAlexa Fluor 568
Cat: K009740P - SAlexa Fluor 568
Summary:
| 【Product name】：Anti-TTL Polyclonal Antibody - SAlexa Fluor 568 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：150465 | 【Swiss Prot】：Q8NG68 |
| 【Tested applications】：IHC,WB,IF,ELISA | |
| 【Recommended dilution】：WB 1:1000-4000. IHC 1:50-500. IF 1:50-500. | |
| 【Immunogen】：Recombinant protein of human TTL | |
| 【Public Immunogen Range】：1-377aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness.
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