Anti-TMEM106A Polyclonal Antibody - SAlexa Fluor 488
Cat: K109436P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-TMEM106A Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：113277 | 【Swiss Prot】：Q96A25 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human TMEM106A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway. Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide. May play a role in inhibition of proliferation and migration.
Verified picture: