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Anti-CNOT9 Polyclonal Antibody - FITC
Cat: K109448P - FITC
Summary:
【Product name】:Anti-CNOT9 Polyclonal Antibody - FITC 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:9125 【Swiss Prot】:Q92600
【Species reactivity】:Human,Rat,Mouse
【Tested applications】:ICC IF
【Recommended dilution】:Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human CNOT9
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.
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