Anti-STYX Polyclonal Antibody
Cat: K109459P
Summary:
| 【Product name】：Anti-STYX Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6815 | 【Swiss Prot】：Q8WUJ0 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human STYX | |
| 【Public Immunogen Range】：55-105/223aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). By binding to the F-box of FBXW7, prevents the assembly of FBXW7 into the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates. Plays a role in spermatogenesis.
Verified picture:
Immunohistochemistry of paraffin-embedded Human melanoma with STYX antibody diluted at 1:100.