Anti-STUB1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K109508P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-STUB1 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：10273 | 【Swiss Prot】：Q9UNE7 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human STUB1 | |
| 【Public Immunogen Range】：1-304aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.
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