Anti-PPM1A Polyclonal Antibody - SAlexa Fluor 350
Cat: K109594P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-PPM1A Polyclonal Antibody - SAlexa Fluor 350 | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：5494 | 【Swiss Prot】：P35813 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human PPM1A | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
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