Anti-DOK4 Polyclonal Antibody
Cat: K109596P
Summary:
| 【Product name】：Anti-DOK4 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：55715 | 【Swiss Prot】：Q8TEW6 |
| 【Tested applications】：WB,IF,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human DOK4 | |
| 【Public Immunogen Range】：1-327aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
Verified picture:
Western blot analysis with DOK4 antibody diluted at 1:2000;Lane: Mouse skeletal muscle.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with DOK4 antibody diluted at 1:100.
Immunofluorescence analysis of HepG2 cells using DOK4 antibody diluted at 1:100.