Anti-VTA1 Polyclonal Antibody - HRP
Cat: K109677P - HRP
Summary:
| 【Product name】：Anti-VTA1 Polyclonal Antibody - HRP | 【Source】：Rabbit |
| 【Isotype】：IgG | |
| 【Gene ID】：51534 | 【Swiss Prot】：Q9NP79 |
| 【Species reactivity】：Human,Rat,Mouse | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human VTA1 | |
| 【Storage】：Store at -20℃, avoid freeze/thaw cycles. | |
Background:
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding.
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