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Anti-MTM1 Polyclonal Antibody - Biotin
Cat: K109863P - Biotin
Summary:
【Product name】:Anti-MTM1 Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG
【Gene ID】:4534 【Swiss Prot】:Q13496
【Species reactivity】:Human,Mouse
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human MTM1
【Storage】:Store at -20℃, avoid freeze/thaw cycles.
Background:
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis. In skeletal muscles, stabilizes MTMR12 protein levels.
Verified picture: