Anti-SARS-CoV Spike S1 Polyclonal Antibody
Cat: K109877P
Summary:
| 【Product name】：Anti-SARS-CoV Spike S1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1489668 | 【Swiss Prot】：P59594 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:10000-20000. | |
| 【Immunogen】：A synthetic peptide of SARS-CoV Spike S1 | |
| 【Public Immunogen Range】：425-475/1255aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
Verified picture:
Western blot analysis with SARS-CoV Spike S1 antibody diluted at 1:15000;Lane:SARS-CoV Spike S1 Protein