Anti-TTK Polyclonal Antibody
Cat: K110574P
Summary:
| 【Product name】：Anti-TTK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：7272 | 【Swiss Prot】：P33981 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human TTK | |
| 【Public Immunogen Range】：1-350aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.
Verified picture:
Western blot analysis with TTK antibody diluted at 1:2000;Lane:HeLa,Jurkat,U-251MG,K-562,A431,MCF7,Mouse brain
Immunohistochemistry of paraffin-embedded Human colorectal cancer using TTK antibody diluted at 1:80