Anti-DHCR24 Polyclonal Antibody
Cat: K110587P
Summary:
| 【Product name】：Anti-DHCR24 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1718 | 【Swiss Prot】：Q15392 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human DHCR24 | |
| 【Public Immunogen Range】：81-430aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis (PubMed:11519011, PubMed:21671375, PubMed:25637936, PubMed:22178193). In addition to its cholesterol-synthesizing activity, can protect cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress (PubMed:11007892, PubMed:22010141). Also protects against amyloid-beta peptide-induced apoptosis (PubMed:11007892).
Verified picture:
Western blot analysis with DHCR24 antibody diluted at 1:2000;Lane:Mouse lung
Immunohistochemistry of paraffin-embedded Human breast cancer using DHCR24 antibody diluted at 1:80
Immunohistochemistry of paraffin-embedded Human testis cancer using DHCR24 antibody diluted at 1:80