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Anti-TRIM2 Polyclonal Antibody - HRP
Cat: K110617P - HRP
Summary:
【Product name】:Anti-TRIM2 Polyclonal Antibody - HRP 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:23321 【Swiss Prot】:Q9C040
【Tested applications】:IHC
【Recommended dilution】:WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200
【Immunogen】:Recombinant protein of human TRIM2
【Public Immunogen Range】:396-745aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.
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