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Anti-GAD2 Polyclonal Antibody - SAlexa Fluor 680
Cat: K110675P - SAlexa Fluor 680
Summary:
【Product name】:Anti-GAD2 Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:2572 【Swiss Prot】:Q05329
【Tested applications】:IHC,WB
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:A synthetic peptide of human GAD2
【Public Immunogen Range】:1-51/585aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
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