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Anti-PPP2R1B Polyclonal Antibody - SAlexa Fluor 555
Cat: K110676P - SAlexa Fluor 555
Summary:
【Product name】:Anti-PPP2R1B Polyclonal Antibody - SAlexa Fluor 555 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5519 【Swiss Prot】:P30154
【Tested applications】:ICC IF
【Recommended dilution】:ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human PPP2R1B
【Public Immunogen Range】:455-505/601aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
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