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Anti-LMCD1 Polyclonal Antibody - SAlexa Fluor 750
Cat: K110706P - SAlexa Fluor 750
Summary:
【Product name】:Anti-LMCD1 Polyclonal Antibody - SAlexa Fluor 750 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:29995 【Swiss Prot】:Q9NZU5
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human LMCD1
【Public Immunogen Range】:75-125/365aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
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