Anti-TPRKB Polyclonal Antibody - Cy7
Cat: K110763P - Cy7
Summary:
| 【Product name】：Anti-TPRKB Polyclonal Antibody - Cy7 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：51002 | 【Swiss Prot】：Q9Y3C4 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human TPRKB | |
| 【Public Immunogen Range】：1-175aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t6A activity of the complex. TPRKB is not required for tRNA modification.
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