Anti-SARS-CoV/CoV-2 Spike S1 Polyclonal Antibody - SAlexa Fluor 488
Cat: K110845P - SAlexa Fluor 488
Summary:
| 【Product name】：Anti-SARS-CoV/CoV-2 Spike S1 Polyclonal Antibody - SAlexa Fluor 488 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1489668 | 【Swiss Prot】：P59594 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of SARS-CoV/CoV-2 Spike S1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
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