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Anti-GRK2 Polyclonal Antibody
Cat: K110860P
Summary:
【Product name】:Anti-GRK2 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:156 【Swiss Prot】:P25098
【Tested applications】:IHC
【Recommended dilution】:IHC 1:100-300.
【Immunogen】:A synthetic peptide of human GRK2
【Public Immunogen Range】:639-689/689aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with GRK2 antibody diluted at 1:200.