Anti-JUP Polyclonal Antibody
Cat: K110874P
Summary:
| 【Product name】：Anti-JUP Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3728 | 【Swiss Prot】：P14923 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:100-300. | |
| 【Immunogen】：A synthetic peptide of human JUP | |
| 【Public Immunogen Range】：695-745/745aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with JUP antibody diluted at 1:200.