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Anti-RAB11FIP3 Polyclonal Antibody
Cat: K110888P
Summary:
【Product name】:Anti-RAB11FIP3 Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:9727 【Swiss Prot】:O75154
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:2000-5000. IHC 1:25-100.
【Immunogen】:A synthetic peptide of human RAB11FIP3
【Public Immunogen Range】:575-625/756aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis. Also required for the structural integrity of the endosomal recycling compartment during interphase. May play a role in breast cancer cell motility by regulating actin cytoskeleton. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
Verified picture:
Western blot analysis with RAB11FIP3 antibody diluted at 1:3000;Lane: Mouse brain.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with RAB11FIP3 antibody diluted at 1:40.
Immunohistochemistry of paraffin-embedded Human thyroid cancer with RAB11FIP3 antibody diluted at 1:40.