Anti-TLE4 Polyclonal Antibody - RBITC
Cat: K110894P - RBITC
Summary:
| 【Product name】：Anti-TLE4 Polyclonal Antibody - RBITC | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7091 | 【Swiss Prot】：Q04727 |
| 【Tested applications】：WB ELISA IHC ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human TLE4 | |
| 【Public Immunogen Range】：190-240/773aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).
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