Anti-FKBP3 Polyclonal Antibody
Cat: K110989P
Summary:
| 【Product name】：Anti-FKBP3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2287 | 【Swiss Prot】：Q00688 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human FKBP3 | |
| 【Public Immunogen Range】：1-224aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Verified picture:
Western blot analysis with FKBP3 antibody diluted at 1:2000;Lane: RAW264.7,HepG2,U251,MCF7.
Immunohistochemistry of paraffin-embedded Human breast cancer with FKBP3 antibody diluted at 1:200.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with FKBP3 antibody diluted at 1:200.