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Anti-WSCD2 Polyclonal Antibody - SAlexa Fluor 680
Cat: K110995P - SAlexa Fluor 680
Summary:
【Product name】:Anti-WSCD2 Polyclonal Antibody - SAlexa Fluor 680 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Octanoic acid-ammonium sulfate precipitation
【Gene ID】:9671 【Swiss Prot】:Q2TBF2
【Tested applications】:WB,IHC
【Recommended dilution】:WB 1:1000-3000. IHC 1:50-200.
【Immunogen】:Recombinant protein of human WSCD2
【Public Immunogen Range】:1-256aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
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