Anti-CBFA2T3 Polyclonal Antibody - SAlexa Fluor 640
Cat: K111062P - SAlexa Fluor 640
Summary:
| 【Product name】：Anti-CBFA2T3 Polyclonal Antibody - SAlexa Fluor 640 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：863 | 【Swiss Prot】：O75081 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human CBFA2T3 | |
| 【Public Immunogen Range】：285-335/653aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
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