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Anti-RAD21 Polyclonal Antibody - SAlexa Fluor 633
Cat: K111064P - SAlexa Fluor 633
Summary:
【Product name】:Anti-RAD21 Polyclonal Antibody - SAlexa Fluor 633 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:5885 【Swiss Prot】:O60216
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human RAD21
【Public Immunogen Range】:540-590/631aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
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