Anti-CHAT Polyclonal Antibody - SAlexa Fluor 594
Cat: K111073P - SAlexa Fluor 594
Summary:
| 【Product name】：Anti-CHAT Polyclonal Antibody - SAlexa Fluor 594 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1103 | 【Swiss Prot】：P28329 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CHAT | |
| 【Public Immunogen Range】：400-450/748aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
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