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Anti-RNF19A Polyclonal Antibody
Cat: K111117P
Summary:
【Product name】:Anti-RNF19A Polyclonal Antibody 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:25897 【Swiss Prot】:Q9NV58
【Tested applications】:IHC
【Recommended dilution】:IHC 1:50-200.
【Immunogen】:A synthetic peptide of human RNF19A
【Public Immunogen Range】:30-80/838aa
【Storage】:Store at -20℃. Avoid freeze/thaw cycles.
Background:
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants.
Verified picture:
Immunohistochemistry of paraffin-embedded Human colorectal cancer with RNF19A antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human testis cancer with RNF19A antibody diluted at 1:100.